Abstract: Dark Matter is one of the pillars of Modern Cosmology, but its nature remains unknown. I will first review the current status of particle Dark Matter, including experimental evidence and theoretical motivations. I will then present some recent developments in indirect searches, in light of recent observational results from the space-based gamma-ray observatory INTEGRAL (energy scale ~ MeV), and from ground-based Air Cherenkov Telescopes such as HESS (energy scale ~ TeV). Finally I discuss the prospects of indirect detection with GLAST, scheduled to be launched in 2007.