Source: UF Health Cancer Center
Juan Guan, Ph.D., an assistant professor in the department of physics in the University of Florida College of Arts and Sciences, has been awarded a $1.9 million grant from the National Institute of General Medical Sciences to explore the mechanisms behind the assembly and regulation of non-canonical biomolecular condensates.
These condensates are tiny membrane-less structures that self-assemble in living cells. They are found in a range of cell types and can exist as protein-only structure or with nucleic acids attached.
“These tiny molecules play an important role in normal cell processes,” said Guan, a member of the Cancer Center’s Mechanisms of Oncogenesis research program. “If they assemble incorrectly within cells, they can cause a variety of problems, including cancer. Our research looks to understand why they assemble incorrectly so we can prevent this.” –> Read more